Clutterbuck D J, Morrison A E, Ludlam C A
Department of Haematology, Royal Infirmary of Edinburgh.
J Clin Pathol. 1995 Sep;48(9):867-8. doi: 10.1136/jcp.48.9.867.
A 59 year old man with longstanding myelofibrosis and previous splenectomy was incidently found to have a large lytic lesion in his left femur which required operative fixation. He had undergone right upper lobectomy for squamous carcinoma of the bronchus five years earlier. Histological analysis of bone reamings showed no evidence of metastatic carcinoma. Osteosclerosis is frequently noted in patients with myelofibrosis but osteolytic lesions are uncommon and may be confused with metastatic malignancy.
一名59岁男性，患有长期骨髓纤维化且曾行脾切除术，偶然发现左股骨有一个大的溶骨性病变，需要手术固定。他在五年前因支气管鳞状癌接受了右上叶切除术。骨钻取物的组织学分析未发现转移癌的证据。骨髓纤维化患者常出现骨硬化，但溶骨性病变并不常见，可能会与转移性恶性肿瘤混淆。
