Rumpf K D, Pichlmayr R
Chirurg. 1982 Feb;53(2):103-8.
A total of 58 patients with chronic pancreatitis had undergone partial duodenopancreatectomy. They were subdivided by histological differentiation according to the presence or absence of calcification and it was found that pancreatic function was far more severely reduced in patients with organ calcification. Exocrine insufficiency was also more marked in these patients, as shown by the weight and fat content of their stool. Enzyme substitution therapy usually has no complications. Endocrine function was also affected, as seen in the preoperative presence of diabetes in 36% of patients with pancreatic stones, three times that of those with sclerosing pancreatitis. Resection of the pancreatic head led to an increase of 12%, i.e. 48%. This indicates that non-resecting operations are preferable in calcifying pancreatitis. Recommendations are made as to the choice of partial duodenopancreatectomy or pancreaticojejunostomy, depending on radiological classification, the course of the disease and the symptoms in each individual case.
共有58例慢性胰腺炎患者接受了十二指肠胰腺部分切除术。根据是否存在钙化,将他们按组织学分化进行细分,结果发现胰腺钙化患者的胰腺功能严重得多。这些患者的外分泌功能不全也更为明显,从他们粪便的重量和脂肪含量可以看出。酶替代疗法通常没有并发症。内分泌功能也受到影响,如术前36%的胰腺结石患者患有糖尿病,这一比例是硬化性胰腺炎患者的三倍。胰头切除术导致增加了12%,即48%。这表明在钙化性胰腺炎中,非切除手术更可取。根据放射学分类、疾病进程和每个病例的症状,就十二指肠胰腺部分切除术或胰空肠吻合术的选择提出了建议。