Mingazzini P L, Malchiodi Albedi F, Blandamura V
Histopathology. 1982 Mar;6(2):235-44. doi: 10.1111/j.1365-2559.1982.tb02718.x.
A villous adenoma of the duodenum was studied histologically and histochemically by semi-thin sections using glycol-methacrylate as embedding medium. All the four epithelial cell types which are present in normal duodenal mucosa (absorptive columnar, goblet, Paneth, endocrine) were found in the tumour, as well as undifferentiated elements. Neutral and acid non-sulphated mucins were detected. Cell type distribution and mucin production varied according to the degree of differentiation. Foci of gastric metaplasia were observed. A possible histogenesis from crypt base stem cell is considered.
采用乙二醇甲基丙烯酸酯作为包埋介质，通过半薄切片对十二指肠绒毛状腺瘤进行了组织学和组织化学研究。在肿瘤中发现了正常十二指肠黏膜中存在的所有四种上皮细胞类型（吸收性柱状细胞、杯状细胞、潘氏细胞、内分泌细胞）以及未分化成分。检测到中性和酸性非硫酸化粘蛋白。细胞类型分布和粘蛋白产生随分化程度而变化。观察到胃化生灶。考虑了源自隐窝基部干细胞的可能组织发生过程。
