Dallosso H M, Murgatroyd P R, James W P
Hum Nutr Clin Nutr. 1982;36C(1):25-39.
Eight young adult males were fed isoenergetic diets of similar composition either in two meals or in six meals per day at defined times. While on each dietary regimen for two weeks the subjects occupied a whole body calorimeter for two 31-h periods, during which they followed a prescribed activity pattern. For each individual the 24-h energy expenditure in the calorimeter was highly reproducible and no discernible effect of meal frequency was observed under these controlled conditions. The total expenditure in the calorimeter on both regimens was substantially less than the energy intake and a progressive small weight gain was observed throughout the 2-week period on the two-meal-a-day system. If feeding frequency alters metabolic efficiency then it does so by mechanisms not readily discernible in a whole body calorimeter.
八名年轻成年男性按照规定时间，每天分两餐或六餐摄入能量相同、成分相似的饮食。在每种饮食方案持续两周的时间里，受试者在全身热量计中停留两个31小时的时间段，在此期间他们遵循规定的活动模式。对于每个个体而言，在热量计中测得的24小时能量消耗具有高度可重复性，并且在这些受控条件下未观察到进餐频率有明显影响。两种饮食方案下在热量计中的总能量消耗均显著低于能量摄入，并且在每日两餐的饮食系统中，在整个两周期间观察到体重逐渐小幅增加。如果进餐频率会改变代谢效率，那么其作用机制在全身热量计中并不容易察觉。
