Wippl G
Padiatr Padol. 1977;12(3):309-12.
The finding of 53% disturbances in synthesizing bacterial antibodies and 88% disturbances in opsonizing in children with purulent meningitis was the reason for therapy with immunglobulins. Intravenous Gammaglobulin (Gammavenin) was used in 26 children with purulent meningitis, 1 ml/kg/d through 3 days. The liquor cell count was in all patients 48 hours after starting of treatment 20% or less, there was no death, 2 children showed neurological defects.
化脓性脑膜炎患儿中发现53%存在合成细菌抗体障碍,88%存在调理作用障碍,这是使用免疫球蛋白进行治疗的原因。26例化脓性脑膜炎患儿使用了静脉注射丙种球蛋白(Gammavenin),剂量为1 ml/kg/d,共3天。开始治疗48小时后,所有患者的脑脊液细胞计数均降至20%或更低,无死亡病例,2例患儿出现神经功能缺损。