Doty D B, Montanaro G D, Carter J G, Moyers J R
J Thorac Cardiovasc Surg. 1982 May;83(5):732-5.
The effect of cardiopulmonary bypass on venous tone was evaluated in 19 patients undergoing coronary artery bypass graft operations. The use of cardiopulmonary bypass with reduction of mean arterial pressure, nonpulsatile blood flow, and emptying of the heart maximally stimulates the sympathoadrenal system and would be expected to cause intense venous constriction. Venous capacitance, however, was reduced by the general effects of the operation, including anesthesia and surgical trauma, while cardiopulmonary bypass was a minor factor in the venous constriction response.
在19例接受冠状动脉搭桥手术的患者中评估了体外循环对静脉张力的影响。使用体外循环并降低平均动脉压、非搏动性血流以及最大程度地排空心脏，会最大程度地刺激交感肾上腺系统，预计会导致强烈的静脉收缩。然而，包括麻醉和手术创伤在内的手术总体影响降低了静脉容量，而体外循环在静脉收缩反应中是一个次要因素。
