Larsen K, Juul A
Laryngoscope. 1982 May;92(5):586-8. doi: 10.1288/00005537-198205000-00024.
Several clinical studies have associated nasal packing in the treatment of epistaxis with hypoxemia on the basis of a possible nasopulmonary reflex. In 10 patients with epistaxis using a pneumatic nasal pack with central airway that allows a limited airflow, no changes in arterial blood gas tensions were observed. Forced expiratory volume measures were also without significant changes. The results indicate that the nasal packs used do not cause any clinically important alveolar hypoventilation or changes in arterial oxygenation. None of the patients had chronic obstructive pulmonary disease, and it is therefore still important to be aware of hypoxemia as a possible complication to nasal packing, especially in old patients with chronic obstructive pulmonary disease, irrespective of the kind of nasal pack used.
多项临床研究基于可能的鼻肺反射，将鼻出血治疗中的鼻腔填塞与低氧血症联系起来。在10例使用带有中央气道、气流受限的气动鼻腔填塞器治疗鼻出血的患者中，未观察到动脉血气张力的变化。用力呼气量测量也无显著变化。结果表明，所使用的鼻腔填塞物不会引起任何具有临床意义的肺泡通气不足或动脉氧合变化。所有患者均无慢性阻塞性肺疾病，因此，仍需注意低氧血症作为鼻腔填塞可能的并发症，尤其是在患有慢性阻塞性肺疾病的老年患者中，无论使用何种鼻腔填塞物。
