Sibai B M, Anderson G D, McCubbin J H
Obstet Gynecol. 1982 Feb;59(2):153-7.
Sixty-seven cases of eclampsia were managed between August 1977 and July 1980. Routinely acquired laboratory tests of these cases have been analyzed. In addition, the group of patients with eclampsia was compared with a group of 24 healthy pregnant women. There was no significant difference in platelet count, serum fibrinogen, and bilirubin values. The activated partial thromboplastin time was abnormal in 42% of patients with eclampsia. There was no clinical evidence of disseminated intravascular coagulation in any patient. Patients with eclampsia had abnormalities of lactic dehydrogenase, alkaline phosphatase, SGOT, uric acid, BUN, and creatinine. However, in any individual patients there was no single test of great clinical usefulness and no test predictive of maternal or fetal outcome. At present the authors recommend complete blood count (including blood smear and platelet count), clot observation, and serum creatinine tests. Liver function tests are reserved for the patient with upper abdominal pain. Additional tests are recommended if the diagnosis of eclampsia is questionable or if an additional disease process is suspected.
1977年8月至1980年7月间共处理了67例子痫患者。对这些病例常规进行的实验室检查结果进行了分析。此外，将子痫患者组与24名健康孕妇组进行了比较。血小板计数、血清纤维蛋白原和胆红素值无显著差异。42%的子痫患者活化部分凝血活酶时间异常。所有患者均无弥散性血管内凝血的临床证据。子痫患者乳酸脱氢酶、碱性磷酸酶、谷草转氨酶、尿酸、尿素氮和肌酐均有异常。然而，对于任何个体患者而言，没有一项检查具有很大的临床实用性，也没有一项检查能够预测母婴结局。目前，作者建议进行全血细胞计数（包括血涂片和血小板计数）、凝血观察和血清肌酐检查。对于有上腹部疼痛的患者，需进行肝功能检查。如果子痫诊断存疑或怀疑有其他疾病过程，则建议进行其他检查。
