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醋酸炔诺酮对卵巢功能活性的影响

[Effect of norethisterone acetate on ovarian functional activity].

作者信息

Fanchenko N D, Anashkina G A, Kuzovkova N A, Adamian L V, Strizhakov A N

出版信息

Probl Endokrinol (Mosk). 1982 Mar-Apr;28(2):38-42.

PMID:7079254
Abstract

Nine women were examined for a period of the 13th to 15th day of the menstrual cycle before and during norethisterone acetate use (10 mg within 10 days). Two-phase character of hormone secretion persisted in 6 of 9 cycles during norethisterone acetate administration. The changed hormone concentration in the 2nd phase and the shortened period of luteinizing hormone functional activity were seen in each cycle. Large individual differences were observed in the blood plasma norethisterone content. No correlation between norethisterone level and the ovarian response pattern was found.

摘要

在服用醋酸炔诺酮(10天内服用10毫克)之前和期间,对9名女性在月经周期的第13至15天进行了检查。在服用醋酸炔诺酮期间,9个周期中有6个周期的激素分泌保持两阶段特征。在每个周期中都观察到第二阶段激素浓度的变化以及促黄体生成素功能活动期的缩短。血浆中醋酸炔诺酮含量存在较大个体差异。未发现醋酸炔诺酮水平与卵巢反应模式之间存在相关性。

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