Brockington I F, Perris C, Kendell R E, Hillier V E, Wainwright S
Psychol Med. 1982 Feb;12(1):97-105. doi: 10.1017/s0033291700043336.
Thirty patients with cycloid psychosis were found among 244 general psychotic and schizo-affective patients studied in London. The main clues to the diagnosis were the presence of "confusion', a pleomorphic clinical picture or an acute onset. Most of the patients were classified as schizophrenic by British psychiatrists and the Catego system, and as schizo-affective or mood-incongruent affective psychotics by the American Research Diagnostic Criteria and DSM-III. There was little overlap between the cycloids and any Anglo-American category, and cycloid psychosis is not synonymous with schizo-affective psychosis. The outcome of the cycloids was better than that of psychotic patients as a whole, and much better than schizophrenia as defined by Catego, Schneider's, Langfeldt's or Carpenter's rules, or by the guidelines set by the International Classification of Diseases. Compared with manic-depressive patients (defined by the presence of mania at some stage), cycloids had more schizophrenic and fewer depressive and manic symptoms. There was a negligible concordance between the diagnosis of cycloid psychosis and the final diagnosis of manic-depressive disease. It is concluded that these patients should not be diagnosed as schizophrenic, but that the relation of cycloid psychosis to manic-depressive disease is not yet resolved.
在伦敦研究的244名普通精神病患者和精神分裂情感障碍患者中,发现了30例环性精神病患者。诊断的主要线索是存在“意识模糊”、多形性临床表现或急性起病。大多数患者根据英国精神病学家和Catego系统被归类为精神分裂症,而根据美国研究诊断标准和《精神疾病诊断与统计手册》第三版(DSM-III)被归类为精神分裂情感障碍或心境不协调的情感性精神病。环性精神病患者与任何英美式分类之间几乎没有重叠,且环性精神病并非精神分裂情感障碍的同义词。环性精神病患者的预后总体上优于精神病患者,且远优于根据Catego、施耐德、朗费尔特或卡彭特的标准,或根据《国际疾病分类》所设定的指南定义的精神分裂症。与躁狂抑郁症患者(定义为在某个阶段出现躁狂症状)相比,环性精神病患者有更多的精神分裂症症状,而抑郁和躁狂症状较少。环性精神病的诊断与躁狂抑郁症的最终诊断之间的一致性可忽略不计。得出的结论是,这些患者不应被诊断为精神分裂症,但环性精神病与躁狂抑郁症之间的关系尚未得到解决。