Paling M R, Spasovsky-Chernick M
Skeletal Radiol. 1982;8(1):63-66. doi: 10.1007/BF00361373.
An unusually high prevalence (10%) of scoliosis is described in a series of 151 patients aged four years and older with cystic fibrosis. The scolioses were of the late onset (juvenile and adolescent) type, being typically thoracic with the curve convex to the right, although there was no significant preference for either sex. No direct relationship was found between the spinal curvature and the severity or distribution of the lung disease, although the worse scolioses tended to occur in patients with relatively severe pulmonary involvement. There was no evidence of metabolic bone disease as a predisposing cause. Some indication of a familial tendency towards scoliosis was apparent, and a genetic or constitutional basis is postulated with an unknown precipitating factor.
在一组151例4岁及以上的囊性纤维化患者中，脊柱侧凸的患病率异常高（10%）。这些脊柱侧凸为迟发型（青少年型），典型表现为胸段脊柱侧凸，凸向右侧，尽管在性别上没有明显的偏好。未发现脊柱弯曲与肺部疾病的严重程度或分布之间存在直接关系，尽管较严重的脊柱侧凸往往发生在肺部受累相对严重的患者中。没有证据表明代谢性骨病是一个诱发原因。有一些迹象表明脊柱侧凸存在家族倾向，并推测有遗传或体质基础，同时存在一个未知的诱发因素。
