Alfredsson L, Karasek R, Theorell T
Soc Sci Med. 1982;16(4):463-7. doi: 10.1016/0277-9536(82)90054-5.
The project was designed to test the assumption that certain psychosocial characteristics of occupational groups are associated with elevated myocardial infarction risk. All cases of myocardial infarction below the age of 65 in men living in the region of greater Stockholm during the years 1974-1976 were identified (deaths as well as survivals) in the official registries of hospitalizations and deaths. For each case two controls without infarction (in younger ages four) matched for age, area of residence and sex were selected randomly from the parish registries. For each case and control (n = 334 and 882, respectively) information was available regarding occupation. The psychosocial characteristics of each one of the 118 occupations were recorded by means of a nation wide interview survey (3876 working men) in 1977. Relative age-adjusted risks of developing a myocardial infarction were calculated for occupations in which many vs occupations in which few subjects reported a given characteristic (50% with most vs 50% with least). Shift work and monotony were associated with significant excess risk. Hectic work was not associated with excess risk by itself but in combination with variables associated with low decision latitude and/or few possibilities for growth it was associated with significant excess risk.
该项目旨在检验一种假设，即职业群体的某些社会心理特征与心肌梗死风险升高有关。1974年至1976年期间，在大斯德哥尔摩地区生活的65岁以下男性心肌梗死病例（包括死亡病例和存活病例）均从官方住院和死亡登记处中识别出来。对于每一例病例，从教区登记处随机选取两名无梗死的对照（年龄较小者为四名），对照在年龄、居住地区和性别方面与病例匹配。对于每一例病例和对照（分别为n = 334和882），均有职业相关信息。1977年通过一项全国性访谈调查（3876名在职男性）记录了118种职业中每一种职业的社会心理特征。计算了报告某一特定特征的受试者较多的职业与报告该特征的受试者较少的职业（最多的50%与最少的50%）发生心肌梗死的相对年龄调整风险。轮班工作和单调乏味与显著的额外风险相关。忙碌的工作本身与额外风险无关，但与决策自由度低和/或成长机会少相关的变量相结合时，它与显著的额外风险相关。
