Sukharevich V I, Iakovleva E P, Shvetsova N N, Medvedeva N G
Antibiotiki. 1978 Oct;23(10):875-9.
When the levorin-producing organism Actinomyces levoris, strain 28 was cultivated on fermentation media under conditions of decreased oxidative-reduction values, a significant decrease in the processes of the culture multiplication and antibiotic production was observed. It was shown that the marked decrease in the catalase activity accompanied by a simultaneous increase in the dehydrogenase activity was one of the causes of the decrease in the processes of the culture multiplication and levorin synthesis. Addition of potassium chloride (0.2 per cent) stimulated the catalase activity and promoted the biomass increase and to some extent the antibiotic production.
当产左旋霉素的微生物左旋放线菌28号菌株在氧化还原值降低的条件下于发酵培养基上培养时,观察到培养物增殖和抗生素产生过程显著减少。结果表明,过氧化氢酶活性显著降低,同时脱氢酶活性增加,这是培养物增殖和左旋霉素合成过程减少的原因之一。添加氯化钾(0.2%)可刺激过氧化氢酶活性,促进生物量增加,并在一定程度上促进抗生素产生。