Payen D M, Levy B I, Menegalli D J, Lajat Y I, Levenson J A, Nicolas F M
Stroke. 1982 May-Jun;13(3):392-8. doi: 10.1161/01.str.13.3.392.
Common carotid blood flow (CCBF) was measured in 11 anesthetised patients without extracranial arterial disease (nine acute subarachnoid haemorrhages and two cases of head injury). The range-gated Doppler flowmeter with an adjustable range-gated time system and a double transducer probe was used to determine diameter, blood velocity, and blood flow of the common carotid artery. Values were, respectively, 5.9 +/- 1.1 mm, 13.8 +/- 6.1 cm . sec-1 and 387 +/- 183 cm3 . min-1. Mean cerebral blood flow (rCBF) measurements were simultaneously made by 133Xenon intra-arterial method, with a value of 22.28 +/- 5.96 ml . min-1 . 100 g. High correlation coefficient was found between CCBF and mean rCBF (r = 0.73, p less than 0.001). The range-gated Doppler flowmeter thus provides a non invasive and easily duplicated method for monitoring cerebral blood flow in anesthetized patients.
在11例无颅外动脉疾病的麻醉患者中（9例急性蛛网膜下腔出血和2例头部损伤）测量了颈总动脉血流量（CCBF）。使用具有可调距离选通时间系统和双换能器探头的距离选通多普勒流量计来测定颈总动脉的直径、血流速度和血流量。其值分别为5.9±1.1毫米、13.8±6.1厘米·秒⁻¹和387±183立方厘米·分钟⁻¹。通过¹³³氙动脉内法同时测量平均脑血流量（rCBF），其值为22.28±5.96毫升·分钟⁻¹·100克。发现CCBF与平均rCBF之间存在高度相关系数（r = 0.73，p＜0.001）。因此，距离选通多普勒流量计为监测麻醉患者的脑血流量提供了一种非侵入性且易于重复的方法。
