Deisenhammer E, Sommer R, Teufl W
Wien Klin Wochenschr. 1982 Jan 22;94(2):42-3.
The significance of serum lipid levels in the assessment of risk in ischaemic cerebral diseases is controversial. The differential investigation of lipoproteins, however, showed that the high-density lipoprotein (HDL) fractions are absolutely or relatively decreased with respect to low-density lipoproteins (LDL) in cerebral infarcts and in transient ischaemic attacks. Raised LDL/HDL ratios were found in this study, as an expression of a relative lowering in HDL, in ischaemic cerebral disease associated with pathological disorders of the large or small cerebral vessels. Hence, it appears that HDL represents a protection factor, not only in the prevention of cardiovascular, but also cerebrovascular disease and a decrease in HDL may be a risk factor.
血清脂质水平在评估缺血性脑疾病风险中的意义存在争议。然而，对脂蛋白的差异研究表明，在脑梗死和短暂性脑缺血发作中，高密度脂蛋白（HDL）组分相对于低密度脂蛋白（LDL）绝对或相对减少。在本研究中，发现与大脑或小脑血管病理紊乱相关的缺血性脑疾病中，LDL/HDL比值升高，这是HDL相对降低的一种表现。因此，似乎HDL不仅在预防心血管疾病中，而且在预防脑血管疾病中都代表一种保护因素，HDL的降低可能是一个风险因素。
