Li J
Zhonghua Yi Xue Za Zhi. 1990 May;70(5):244-7, 18.
Significant decrease of serum high density lipoprotein cholesterol (HDL-C) in cerebrovascular diseases (CVD) was mentioned in our previous report (1981). The results of further studies on lipoprotein patterns of 425 cases of various CVD are presented. Reduction of HDL level (including both HDL-C and apolipoprotein A1) was observed not only in the group of patients hospitalized due to apoplexy (cerebral infarction or hemorrhage), but also in patients under normal living conditions. The latter group included patients with cerebrovascular insufficiency, transient ischemic attacks mild residual neuro-muscular symptoms after recovery from stroke. It is surmised that HDL lowering was present early in CVD cases before attack of apoplexy and is one of the risk factors of CVD The degree of HDL lowering in CVD groups were much more marked than that in our reported cases of coronary heart disease (CHD). The prominent change of lipoprotein pattern in CHD group was elevation of apoB and total cholesterol (TC); however, apoB and TC were approximately normal or significantly lower in certain CVD groups.
我们之前的报告（1981年）提到脑血管疾病（CVD）患者血清高密度脂蛋白胆固醇（HDL-C）显著降低。本文展示了对425例各类脑血管疾病患者脂蛋白模式的进一步研究结果。不仅在因中风（脑梗死或脑出血）住院的患者组中观察到HDL水平（包括HDL-C和载脂蛋白A1）降低，在正常生活条件下的患者中也观察到了这种情况。后一组包括脑血管功能不全、短暂性脑缺血发作以及中风恢复后有轻度残留神经肌肉症状的患者。据推测，在中风发作前，CVD患者早期就存在HDL降低的情况，且这是CVD的危险因素之一。CVD组中HDL降低的程度比我们报告的冠心病（CHD）病例更为明显。CHD组脂蛋白模式的显著变化是载脂蛋白B（apoB）和总胆固醇（TC）升高；然而，在某些CVD组中，apoB和TC大致正常或显著降低。
