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人体胃窦切除术后胃酸分泌及血清胃泌素水平

Secretion of gastric acid and serum gastrin following antral exclusion in man.

作者信息

Pedersen J H, Wille-Jørgensen P

出版信息

Acta Chir Scand. 1980;146(8):615-7.

PMID:7223301
Abstract

Serum gastrins and secretion of gastric acid were determined in one patient with recurrent ulcer following a Billroth II gastrectomy with incomplete excision of gastric antrum. Antral exclusion resulted in a modest rise in serum gastrin from 86 pg/ml to 141 pg/ml. This rise in gastrin seemed responsible for an augmented Basal production of acid and the ulcer diathesis as excision of the antral remnant 18 months later resulted in normogastrinaemia, normal gastric acid secretion and disappearance of the ulcer diathesis.

摘要

对1例毕Ⅱ式胃切除术后胃窦未完全切除而发生复发性溃疡的患者,测定了血清胃泌素和胃酸分泌情况。胃窦旷置术使血清胃泌素从86 pg/ml适度升高至141 pg/ml。胃泌素的这种升高似乎是基础胃酸分泌增加和溃疡素质的原因,因为18个月后切除残留胃窦导致了正常胃泌素血症、正常胃酸分泌以及溃疡素质消失。

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