Viehweg B, Ruckhäberle K E, Vogtmann C
Zentralbl Gynakol. 1982;104(4):221-31.
An analysis was made of 151 twin pregnancies, in 1975, 1978 and 1979, to study the effectiveness of obstetrico-neonatological attention to bigeminal pregnancies in a premature infant centre. -- Significant rise in early detection of bigeminal pregnancy due to much wider use of ultrasonic diagnosis and intensification of hospital treatment have drastically reduced the number of extremely immature twin births by delaying delivery to somewhere between the 34th and 36th weeks of gravidity. With the use of tocolysis nearly unchanged throughout the period of observation, change in average gestational age at birth should be interpreted primarily as the result of more long-time prepartum hospitalisation, with attention being offered for periods of more than three weeks. This conclusion was supported by unsatisfactory results regarding average gestational age and birth weight, following exclusive outpatient attention to women with bigeminal pregnancies. Improvement of foetal prognosis was found to depend primarily on proper therapeutic approach to prematurity. -- The authors' own experience differed from reports of other workers, in that the rate of hypotrophy declined in the wake of intensive prepartum care. Substantial reduction of the gap between average birth weights of first multiple foetuses and those of second multiple foetuses as well as declining differences between average birth weights of heavier twins, on the one hand, and those of less heavy twins, on the other, were recorded from all gestational age groups and attributed to improvement in intra-uterine care for all multiple foetuses due to intensified treatment. -- Significant rise in survival rates (after deduction of all foetal loss up to the 28th day of age) of all premature twins is considered an expression of increasingly improving life chances of twins, in general. It was based on growing numbers of highly immature survivors, but even more on significant rise in the number of premature survivors between the 34th and 36th weeks of gestation.
1975年、1978年和1979年对151例双胎妊娠进行了分析,以研究在一个早产儿中心对双胎妊娠进行产科 - 新生儿护理的效果。——由于超声诊断的广泛应用和医院治疗的强化,双胎妊娠的早期发现显著增加,通过将分娩推迟到妊娠34至36周之间,极大地减少了极不成熟双胎的出生数量。在整个观察期间,宫缩抑制剂的使用几乎没有变化,出生时平均孕周的变化应主要解释为产前住院时间延长的结果,住院时间超过三周。对于双胎妊娠妇女仅进行门诊护理后,平均孕周和出生体重的结果不理想,这支持了这一结论。发现胎儿预后的改善主要取决于对早产的适当治疗方法。——作者自己的经验与其他研究者的报告不同,即产前强化护理后发育迟缓率下降。从所有孕周组都记录到,一方面,第一胎儿与第二胎儿平均出生体重之间的差距大幅缩小,另一方面,较重双胎与较轻双胎平均出生体重之间的差异也在缩小,这归因于强化治疗使所有多胎儿的宫内护理得到改善。——所有早产双胎的存活率(扣除直至出生后第28天的所有胎儿损失后)显著提高,这被认为总体上表明双胎的生存机会在不断改善。这是基于极不成熟幸存者数量的增加,但更多是基于妊娠34至36周之间早产幸存者数量的显著增加。