Strasberg S M, Ilson R G, Petrunka C N
Am J Physiol. 1982 May;242(5):G475-80. doi: 10.1152/ajpgi.1982.242.5.G475.
The use of [14C]erythritol for the quantitative assessment of hepatic bile formation has been studied in baboons using sodium taurocholate to generate canalicular bile flow. It has been found that increments in [14C]erythritol clearance are equal to taurocholate-induced increments in bile flow, but there was no change in [14C]erythritol clearance when bile flow was increased by secretin. No evidence was found to support the view that bile acids affect bile acid-independent bile flow.
在狒狒中使用[14C]赤藓糖醇来定量评估肝脏胆汁生成，通过牛磺胆酸钠来产生胆小管胆汁流。研究发现，[14C]赤藓糖醇清除率的增加与牛磺胆酸钠诱导的胆汁流增加相等，但当通过促胰液素增加胆汁流时，[14C]赤藓糖醇清除率没有变化。没有证据支持胆汁酸影响不依赖胆汁酸的胆汁流这一观点。
