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2-异丁基-3-甲氧基吡嗪特异性嗅觉受体的鉴定。

Identification of a specific olfactory receptor for 2-isobutyl-3-methoxypyrazine.

作者信息

Pelosi P, Baldaccini N E, Pisanelli A M

出版信息

Biochem J. 1982 Jan 1;201(1):245-8. doi: 10.1042/bj2010245.

Abstract

2-Isobutyl-3-methoxypyrazine, a potent bell-pepper odorant, binds to cow olfactory mucosa homogenate. The receptor is saturable in the micromolar range and is competitively inhibited by other bell-pepper odourants, but not by other pyrazines of different odours. Other tissues do not bind 2-isobutyl-3-methoxypyrazine at a significant extent. We suggest that this receptor is involved in odour discrimination.

摘要

2-异丁基-3-甲氧基吡嗪是一种具有强烈甜椒气味的物质,它能与牛嗅觉黏膜匀浆结合。该受体在微摩尔范围内可饱和,且会受到其他甜椒气味物质的竞争性抑制,但不受其他具有不同气味的吡嗪类物质的抑制。其他组织在很大程度上不会结合2-异丁基-3-甲氧基吡嗪。我们认为该受体参与气味辨别。

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