A clinico-morphological analysis of 6 cases of proliferating myositis is presented. The patients varied in ages from 31 to 59 years. All the patients reported an extremely rapid growth of swellings: the period from the moment of the "tumour" detection to the operation was within 1 month, and in 4 cases 2 weeks. The main features of the microscopic structure of proliferating myositis included marked proliferation of fibroblasts and random arrangement of large cells with basophilic cytoplasm resembling rhabdomyoblasts and ganglionic cells. A detailed clinico-morphological analysis of the disease permits to differentiate proliferating myositis from similar soft tissue neoplasms (embryonal rhabdomyosarcoma, ganglioneuroblastoma, fibrosarcoma, extraabdominal desmoid, nodular fascitis).
本文对6例增生性肌炎进行了临床形态学分析。患者年龄在31至59岁之间。所有患者均报告肿物生长极快:从“肿瘤”发现到手术的时间在1个月内,4例为2周。增生性肌炎微观结构的主要特征包括成纤维细胞明显增生以及大细胞随机排列,这些大细胞具有嗜碱性细胞质,类似横纹肌母细胞和神经节细胞。对该疾病进行详细的临床形态学分析有助于将增生性肌炎与类似的软组织肿瘤(胚胎性横纹肌肉瘤、神经母细胞瘤、纤维肉瘤、腹外硬纤维瘤、结节性筋膜炎)区分开来。