Wieslander J B, Aberg M, Dougan P
Br J Plast Surg. 1982 Apr;35(2):158-62. doi: 10.1016/0007-1226(82)90155-2.
Microvascular anastomoses were performed under standardized conditions on the central artery of the ear in 8 rabbits. In all, 6 end-to-end and 5 end-in-end anastomoses were carried out. In 3 rabbits, one type of anastomosis was performed on each ear thus permitting simultaneous comparison of both types. Other than the local application of lidocaine, no anticoagulants or vasodilating agents were used. 32P labelled platelets were injected intravenously 2 hours before microvascular anastomoses were performed. All end-to-end anastomoses showed a rapid increase in radioactivity immediately after removal of the vessel clamps. The activity reached a peak some 300-600% above the initial value after approximately 30 minutes and then decreased. The patent vessels in the end-in-end group showed no increase in platelet activity and the difference between the two groups was significant during the first two hours. The results are interpreted as showing that platelet accumulation in patent vessels is more pronounced in end-to-end than in end-in-end anastomoses.
在8只家兔的耳中央动脉上，于标准化条件下进行微血管吻合术。总共进行了6例端端吻合和5例端对端吻合。在3只家兔中，每只耳朵进行一种类型的吻合，从而可以同时比较两种类型。除局部应用利多卡因外，未使用抗凝剂或血管扩张剂。在进行微血管吻合术2小时前，静脉注射32P标记的血小板。所有端端吻合在移除血管夹后立即显示放射性迅速增加。大约30分钟后，活性达到初始值以上约300 - 600%的峰值，然后下降。端对端组的通畅血管未显示血小板活性增加，两组之间在前两小时的差异显著。结果表明，在端端吻合中，通畅血管中的血小板聚集比端对端吻合中更明显。
