Cocconi G, DeLisi V, Di Blasio B
Cancer Treat Rep. 1982 Jun;66(6):1263-6.
In a prospective randomized study, 53 patients with advanced gastric cancer previously untreated by chemotherapy were randomly assigned to treatment with 5-FU alone or combined with mitomycin and cytarabine (MFC). The response rate with MFC was higher (28%) than with 5-FU alone (21%). The difference, however, was not statistically significant. Median response duration was practically identical with 5-FU (16 weeks) and MFC (17 weeks). There was no difference in median survival between the two groups (39 and 43 weeks, respectively).
在一项前瞻性随机研究中，53例先前未接受过化疗的晚期胃癌患者被随机分配接受单独使用5-氟尿嘧啶或联合丝裂霉素和阿糖胞苷（MFC）治疗。MFC组的缓解率（28%）高于单独使用5-氟尿嘧啶组（21%）。然而，差异无统计学意义。5-氟尿嘧啶组和MFC组的中位缓解持续时间实际相同（分别为16周和17周）。两组的中位生存期无差异（分别为39周和43周）。
