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饮酒及其他生活方式因素对在职人群血压水平及高血压患病率的影响。

Effects of alcohol use and other aspects of lifestyle on blood pressure levels and prevalence of hypertension in a working population.

作者信息

Arkwright P D, Beilin L J, Rouse I, Armstrong B K, Vandongen R

出版信息

Circulation. 1982 Jul;66(1):60-6. doi: 10.1161/01.cir.66.1.60.

Abstract

The relationship between alcohol consumption and blood pressure was studied in 491 males, ages 20-45 years, who volunteered to complete a health questionnaire and submit to standardized measurements of blood pressure, heart rate and body size. Average weekly alcohol consumption correlated with systolic pressure (r = 0.18) but not diastolic pressure. Systolic pressure increased progressively with increasing alcohol consumption, with no obvious threshold effect. In moderate and heavy drinkers (53% of the population studied), the prevalence of systolic hypertension (greater than or equal to 140 mm Hg) was four times that of teetotalers. The effect of alcohol on systolic blood pressure was independent of the effects of age, obesity, cigarette smoking and physical activity. Ex-heavy drinkers had blood pressures similar to those of teetotalers, suggesting that the effect of alcohol is reversible. Cigarette smokers had lower diastolic pressures than nonsmokers, an effect independent of obesity. The linear correlation between alcohol consumption and systolic blood pressure and the lower blood pressures in exdrinkers suggest a cause-and-effect relationship. The results indicate that alcohol ranks close to obesity as a potentially preventable cause of hypertension in the community.

摘要

对491名年龄在20至45岁之间的男性进行了酒精摄入量与血压关系的研究,这些男性自愿填写健康问卷并接受血压、心率和体型的标准化测量。平均每周酒精摄入量与收缩压相关(r = 0.18),但与舒张压无关。收缩压随着酒精摄入量的增加而逐渐升高,没有明显的阈值效应。在中度和重度饮酒者(占研究人群的53%)中,收缩期高血压(大于或等于140毫米汞柱)的患病率是戒酒者的四倍。酒精对收缩压的影响独立于年龄、肥胖、吸烟和体育活动的影响。曾经的重度饮酒者的血压与戒酒者相似,这表明酒精的影响是可逆的。吸烟者的舒张压低于不吸烟者,这种影响与肥胖无关。酒精摄入量与收缩压之间的线性相关性以及戒酒者较低的血压表明存在因果关系。结果表明,在社区中,酒精作为高血压的一个潜在可预防原因,其地位与肥胖相近。

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