Friedman M, Thoresen C E, Gill J J, Ulmer D, Thompson L, Powell L, Price V, Elek S R, Rabin D D, Breall W S, Piaget G, Dixon T, Bourg E, Levy R A, Tasto D L
Circulation. 1982 Jul;66(1):83-92. doi: 10.1161/01.cir.66.1.83.
We studied 1035 consecutive postinfarction patients to determine the feasibility of altering type A behavior and the effect such alteration might have on subsequent rates of infarction and cardiovascular death. Approximately 300 subjects were enrolled in small groups and primarily received cardiologic counseling on the usually accepted coronary risk factors. Six hundred subjects received, in addition to cardiologic counseling, advice and instructions designed to diminish the intensity of their type A behavior. The remaining subjects, serving as controls, received no counseling, but were examined and interviewed annually, as were those who dropped out of counseling groups. More than 98% of the 1035 subjects exhibited moderate-to-severe type A behavior during a videotaped structured interview. After the first year of this 5-year study, the rates of infarction and cardiovascular death were lower (p less than 0.01 and p less than 0.05, respectively) among subjects who received both cardiologic and behavioral counseling than among the control subjects. The rate of nonfatal infarction was lower (p less than 0.05) among subjects who received behavioral counseling than among those who received only cardiologic counseling or those who dropped out of either counseling group. The circumstances that most often preceded recurrent infarction or cardiovascular death were emotional crisis, excess physical activity, ingestion of a single fatty meal or a combination of these phenomena.
我们研究了1035例连续的心肌梗死后患者,以确定改变A型行为的可行性以及这种改变可能对随后的梗死发生率和心血管死亡率产生的影响。大约300名受试者被分成小组纳入研究,主要接受了关于通常公认的冠状动脉危险因素的心脏病学咨询。除心脏病学咨询外,600名受试者还接受了旨在减轻其A型行为强度的建议和指导。其余受试者作为对照组,未接受任何咨询,但与退出咨询组的受试者一样,每年接受检查和访谈。在一次录像结构化访谈中,1035名受试者中超过98%表现出中度至重度A型行为。在这项为期5年的研究的第一年之后,接受心脏病学和行为咨询的受试者的梗死发生率和心血管死亡率低于对照组(分别为p<0.01和p<0.05)。接受行为咨询的受试者的非致命性梗死发生率低于仅接受心脏病学咨询的受试者或退出任何一个咨询组的受试者(p<0.05)。复发性梗死或心血管死亡最常发生的情况是情绪危机、过度体力活动、摄入一顿高脂肪餐或这些现象的综合。