Gill C C, King H C, Lytle B W, Cosgrove D M, Golding L A, Loop F D
Circulation. 1982 Aug;66(2 Pt 2):I147-9.
Forty-three patients, nine men and 34 women, mean age 60 years (range 23-81 years), who had small aortic roots underwent aortic valve replacement with a St. Jude Medical valve. Preoperatively, five patients were in New York Heart Association (NYHA) class I, 19 were in class II, 15 were in class III and four were in class IV. In 30 of 36 patients with aortic stenosis, the mean gradient was 102 mm Hg (range 52-175 mm Hg; in six patients with aortic stenosis, the gradient was not measured. Seven patients underwent surgery for aortic regurgitation. Ten patients received a 19-mm valve, 29 a 21-mm valve and nine a 23-mm valve. Two patients (4.6%) died in the hospital, one immediately postoperatively and the other from low cardiac output 9 days postoperatively. There are 670 patient-months of follow-up (mean 17 months). Thirty-six patients are NYHA class I and two patients are in class II. There have been no thromboembolic episodes in 605 months of follow-up for patients maintained on warfarin. There was one partial valve thrombosis among eight patients being managed without warfarin. No mechanical valve failures have occurred. The St. Jude Medical valve provides a satisfactory early result when used to replace the aortic valve of patients who have a small aortic root.
43例患者（9例男性，34例女性），平均年龄60岁（范围23 - 81岁），主动脉根部较小，接受了圣犹达医疗公司瓣膜的主动脉瓣置换术。术前，5例患者为纽约心脏协会（NYHA）心功能I级，19例为II级，15例为III级，4例为IV级。36例主动脉瓣狭窄患者中，30例的平均跨瓣压差为102 mmHg（范围52 - 175 mmHg）；6例主动脉瓣狭窄患者未测量跨瓣压差。7例患者因主动脉瓣关闭不全接受手术。10例患者植入19 mm瓣膜，29例植入21 mm瓣膜，9例植入23 mm瓣膜。2例患者（4.6%）在医院死亡，1例术后即刻死亡，另1例术后9天因低心排血量死亡。随访时间共670患者 - 月（平均17个月）。36例患者为NYHA心功能I级，2例为II级。接受华法林治疗的患者在605个月的随访中未发生血栓栓塞事件。8例未接受华法林治疗的患者中有1例发生部分瓣膜血栓形成。未发生机械瓣膜故障。圣犹达医疗公司瓣膜用于置换主动脉根部较小患者的主动脉瓣时，早期结果令人满意。
