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海洛因成瘾者对使用LAAM进行六周戒毒治疗的反应。

Heroin addict responses to six weeks of detoxification with LAAM.

作者信息

Sorensen J L, Hargreaves W A, Weinberg J A

出版信息

Drug Alcohol Depend. 1982 Feb;9(1):79-87. doi: 10.1016/0376-8716(82)90027-8.

DOI:10.1016/0376-8716(82)90027-8
PMID:7084024
Abstract

This paper describes the range of experience of 28 heroin addicts who received LAAM instead of methadone over six weeks in an outpatient detoxification program. Four patients are singled out to illustrate the variety of response during withdrawal, temporary abstinence from drugs, and social adjustment. The paper explores the motivation of patients and both their physical and subjective responses to the detoxification attempt. By describing a variety of patients, the paper documents clinical responses that cannot be communicated in statistical summaries or single-case reports. Overall, the cases illustrate the difficulties of brief-stay outpatient detoxification from heroin. Clinicians should expect to see only small steps toward rehabilitation during a patient's attempt to taper from opiates, but even minimal progress may justify the use of detoxification programs as a link between "street life" and the decision to enter long-term treatment.

摘要

本文描述了28名海洛因成瘾者在门诊戒毒项目中接受长效美沙酮(LAAM)而非美沙酮进行六周治疗的一系列经历。挑选出四名患者以说明戒毒期间、暂时戒毒及社会适应过程中的各种反应。本文探讨了患者的动机以及他们对戒毒尝试的身体和主观反应。通过描述各类患者,本文记录了无法在统计摘要或单病例报告中传达的临床反应。总体而言,这些病例说明了海洛因短期门诊戒毒的困难。临床医生应预期在患者逐渐减少阿片类药物用量的过程中,康复进展甚微,但即使是最小的进展也可能证明戒毒项目作为“街头生活”与决定接受长期治疗之间的纽带是合理的。

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1
Heroin addict responses to six weeks of detoxification with LAAM.海洛因成瘾者对使用LAAM进行六周戒毒治疗的反应。
Drug Alcohol Depend. 1982 Feb;9(1):79-87. doi: 10.1016/0376-8716(82)90027-8.
2
Withdrawal from heroin in three or six weeks. Comparison of methadyl acetate and methadone.三到六周内停用海洛因。醋酸美沙多与美沙酮的比较。
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NIDA Res Monogr. 1976 Jul(8):39-51.
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Acceptability of methadyl acetate (LAAM) as compared with methadone in a treatment program for heroin addicts.在一项针对海洛因成瘾者的治疗项目中,醋酸美沙多(LAAM)与美沙酮相比的可接受性。
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