Bruynzeel D P, Boonk W J, van Ketel W G
Derm Beruf Umwelt. 1982;30(1):16-20.
6 out of 9 patients with allergic contact dermatitis of the hands were successfully treated with oral methoxsalenultraviolet-A (PUVA) photochemotherapy. Clearing the dermatitis symptoms of the hands was achieved with an average of 23 treatments (150 J/cm2). To maintain the initial results a rather frequent maintenance treatment--usually once a week--was necessary. Longer treatment intervals resulted in a relapse of the dermatitis. This made continuous treatment necessary. In one patient treatment was stopped, and he remained clear for 17 weeks. The influence of PUVA on the allergic status of the patients is supposed to be a local effect. PUVA proves to be a valuable addition in the treatment of occupational hand dermatitis.
9例手部过敏性接触性皮炎患者中，有6例通过口服甲氧沙林联合长波紫外线（PUVA）光化学疗法成功治愈。平均经过23次治疗（150 J/cm²）后手部皮炎症状消退。为维持初始疗效，需要相当频繁的维持治疗——通常每周一次。治疗间隔时间延长会导致皮炎复发。这使得持续治疗成为必要。有1例患者停止治疗，其病情缓解状态维持了17周。PUVA对患者过敏状态的影响推测为局部作用。PUVA被证明是治疗职业性手部皮炎的一种有效辅助方法。
