Pausch J, Jäckle B, Schmidt D, Mann W
Dtsch Med Wochenschr. 1982 Jul 23;107(29-30):1143-7. doi: 10.1055/s-2008-1070091.
In a 51-year-old patient with non-syphilitic interstitial keratitis and disturbances of inner ear function (Cogan's syndrome) the course of the disease could be followed for 8 years. Organ manifestations which indicated generalised vascular disease were present in accordance with reports in the literature of this rare syndrome. In addition to multiple digital arterial occlusions, recurrent pulmonary infiltrations were observed which have not previously been described in connection with this syndrome. With the exception of the inner ear hearing loss the symptoms could be improved by systemic administration of corticosteroids and azathioprine. The patient remained free of recurrence for over three years.
在一名患有非梅毒性间质性角膜炎和内耳功能障碍（科根综合征）的51岁患者中，对该疾病的病程进行了8年的跟踪观察。与该罕见综合征的文献报道一致，出现了提示全身性血管疾病的器官表现。除了多发性指动脉闭塞外，还观察到反复出现的肺部浸润，此前尚未有关于该综合征的相关描述。除内耳听力损失外，通过全身性给予皮质类固醇和硫唑嘌呤，症状可得到改善。该患者三年多未复发。
