大鼠皮脂分泌分化的新生期关键时期研究。
Studies on the critical period of neonatal life for the differentiation of sebum secretion in rats.
作者信息
Toh Y C
出版信息
Endokrinologie. 1982 Feb;79(1):7-12.
Sprague-Dawley rats were castrated at the age of 1, 3, 5, 10 or 21 days. A control group of male and female rats were also included for comparison. The secretion rate of sebum was assessed from the amount of skin-surface lipids that could be extracted by acetone and which had been produced during 2 days. Sebum production increased with age, particularly in male rats. Castration of male rats at the age of 1, 3, 5, or 10 days showed no differences from female rats in sebum secretion when measured at the age of 80 days. On the other hand, male rats that had been castrated at the age of 21 days secreted significantly more sebum than female rats.
将1日龄、3日龄、5日龄、10日龄或21日龄的斯普拉格-道利大鼠进行去势。还纳入了一组雄性和雌性对照大鼠用于比较。通过丙酮可提取的、在2天内产生的皮肤表面脂质的量来评估皮脂分泌率。皮脂分泌量随年龄增加，尤其是雄性大鼠。在1日龄、3日龄、5日龄或10日龄对雄性大鼠进行去势，在80日龄测量时，其皮脂分泌与雌性大鼠无差异。另一方面，21日龄去势的雄性大鼠分泌的皮脂明显多于雌性大鼠。
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