Lawrence M
Environ Health Perspect. 1982 Apr;44:9-13. doi: 10.1289/ehp.82449.
The transduction from sound vibrations to a nerve ending stimulus takes place in the organ of Corti. This process, resulting from fluid particle movement of a magnitude equivalent to the dimensions of the electron cloud around an atom, involves more than a simple deformation of the sensory cell. The fluid environment of these cells must be such that it provides sufficient oxygen and nutrients for the cells' survival and at the same time maintains a condition to enhance the biophysical process. The spiral capillaries beneath the tunnel of Corti furnish the metabolites for the Cortilymph surrounding the sensory cells. The capillaries of the stria vascularis provide this structure, an organ in its own right, so that it can maintain the high potassium concentration and positive potential of endolymph which are necessary for the transduction process. The stria vascularis itself and its blood supply and the sensory cells and their blood supply are all vulnerable to attack by various toxic agents, thus altering the homeostatic condition and resulting in a hearing loss.
从声音振动到神经末梢刺激的转换发生在柯蒂氏器中。这个过程源于与围绕原子的电子云尺寸相当的流体粒子运动，它涉及的不仅仅是感觉细胞的简单变形。这些细胞的流体环境必须既能为细胞的存活提供足够的氧气和营养物质，又能维持一种增强生物物理过程的条件。柯蒂氏管下方的螺旋毛细血管为围绕感觉细胞的内淋巴提供代谢产物。血管纹的毛细血管为这个本身就是一个器官的结构提供支持，使其能够维持内淋巴的高钾浓度和正电位，而这是转换过程所必需的。血管纹本身及其血液供应、感觉细胞及其血液供应都容易受到各种有毒物质的攻击，从而改变体内平衡状态并导致听力损失。
