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哺乳期大鼠乳腺中三酰甘油的立体特异性生物合成。

Stereospecific biosynthesis of triacylglycerols in mammary glands from lactating rats.

作者信息

Cooper S M, Grigor M R

出版信息

Biochem J. 1978 Aug 15;174(2):659-62. doi: 10.1042/bj1740659.

Abstract

Microsomal plus cytosol preparations from the mammary gland of lactating rats are capable of incorporating palmitic acid and oleic acid into triacylglycerols. These triacylglycerols are similar in structure to those found in rat milk, where palmitic acid tends to be confined to the sn-2-position of the glycerol. Both glycerol 3-phosphate and dihydroxyacetone phosphate function as acyl acceptors. The enzymic synthesis of triacylglycerols appears in late pregnancy, increases rapidly during early lactation, but disappears within 3 days of weaning.

摘要

来自泌乳大鼠乳腺的微粒体加胞质溶胶制剂能够将棕榈酸和油酸掺入三酰甘油中。这些三酰甘油在结构上与大鼠乳汁中的三酰甘油相似,其中棕榈酸倾向于局限于甘油的sn-2位。3-磷酸甘油和磷酸二羟丙酮均作为酰基受体发挥作用。三酰甘油的酶促合成在妊娠后期出现,在泌乳早期迅速增加,但在断奶后3天内消失。

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Triglyceride structure of human milk fat.人乳脂肪的甘油三酯结构
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