Sonnenberg A, Erckenbrecht J, Peter P, Niederau C
Gastroenterology. 1982 Aug;83(2):430-4.
The target appearance of grey scale ultrasound is thought to be a characteristic sign of gastrointestinal wall thickening. It consists of a strong echogenic center surrounded by a sonolucent rim. In a prospective controlled study, the sensitivity and specificity of the ultrasonic B-scan for Crohn's disease were investigated. Fifty-one patients with Crohn's disease and 124 control subjects were studied. Sensitivity and specificity of the ultrasonic target appearance for Crohn's disease were 76% and 88%, respectively. When additional ultrasonic signs of inflammatory bowel disease were considered, sensitivity and specificity rose to 84% and 91%, respectively. Both colon and ileum were affected in 85% of the true-positive and in 8% of the false-negative targets. The Crohn's disease activity index was 213 +/- 136 in patients with true-positive targets and 167 +/- 118 in patients with false-negative target appearances. Most false-positive target phenomena arose from gastrointestinal tumors. It is concluded that ultrasound is a suitable complementary method for the detection of Crohn's disease.
灰阶超声的目标表现被认为是胃肠道壁增厚的特征性征象。它由一个强回声中心和周围的无回声边缘组成。在一项前瞻性对照研究中，对超声B超检查克罗恩病的敏感性和特异性进行了研究。研究了51例克罗恩病患者和124名对照受试者。超声目标表现对克罗恩病的敏感性和特异性分别为76%和88%。当考虑炎症性肠病的其他超声征象时，敏感性和特异性分别升至84%和91%。在85%的真阳性和8%的假阴性目标中，结肠和回肠均受累。真阳性目标患者的克罗恩病活动指数为213±136，假阴性目标表现患者的克罗恩病活动指数为167±118。大多数假阳性目标现象源于胃肠道肿瘤。结论是超声是检测克罗恩病的一种合适的辅助方法。
