Hall M R
Gerontology. 1982;28 Suppl 1:18-24. doi: 10.1159/000212570.
The incidence of adverse reaction to drugs and of drug interaction increases with age. The types of interaction which may occur are described. The mechanisms underlining pharmacokinetic and pharmacodynamic interactions are described and examples of common drug interactions which may occur in the elderly are given. It is emphasised that the elderly may need to take several drugs for the maintenance of good health and the potential danger of the part played by interaction must be recognised.
药物不良反应和药物相互作用的发生率会随着年龄的增长而增加。文中描述了可能发生的相互作用类型。阐述了药代动力学和药效学相互作用背后的机制，并列举了老年人中可能出现的常见药物相互作用的例子。需要强调的是，老年人可能需要服用多种药物来维持健康，必须认识到药物相互作用所带来的潜在风险。
