Krovetz L J, Brenner J I, Polanyi M, Ostrowski D
Br Heart J. 1978 Sep;40(9):1010-3. doi: 10.1136/hrt.40.9.1010.
An improved fibreoptic in vivo haemoreflection system has been used in over 200 patients. Continuous recording of oxygen saturation while moving the catheter permits measurement of simultaneous pressure and oxygen saturation at almost an unlimited number of sites through the right heart. The oxygen saturation can be continuously monitored and the response is sufficiently fast to permit investigation of changes in oxygen saturation during portions of the cardiac cycle. Dye dilution curves have been recorded from over 200 patients. The only blood withdrawn for the dye dilution curve was the 3 ml needed for checking the calibration of the instrument. We have found that the calibration is extremely stable. In some instances where it has been deemed impractical to obtain blood for calibration, the calibration factor for each catheter may be used. In any case, the calibration check is performed at the end of the study and does not present problems of sterility. The calibration factor may yield a correction factor which then applies uniformly to all the cardiac output values obtained during the study.
一种改进的光纤体内血液反射系统已应用于200多名患者。在移动导管时连续记录氧饱和度，可通过右心在几乎无限数量的部位同时测量压力和氧饱和度。氧饱和度可被连续监测，其响应速度足够快，以允许研究心动周期各部分期间氧饱和度的变化。已从200多名患者记录了染料稀释曲线。用于染料稀释曲线的唯一采血是检查仪器校准所需的3毫升血液。我们发现校准极其稳定。在某些情况下，若认为获取用于校准的血液不切实际，可使用每个导管的校准系数。无论如何，校准检查在研究结束时进行，且不存在无菌问题。校准系数可能会产生一个校正因子，该因子随后统一应用于研究期间获得的所有心输出量值。
