使用光纤导管对新生儿进行连续中心静脉血氧饱和度（ScvO2）测量。
Continuous central venous oxygen saturation (ScvO2) measurement using a fibre optic catheter in newborn infants.
作者信息
van der Hoeven M A, Maertzdorf W J, Blanco C E
机构信息
Department of Neonatology, University of Limburg, Maastricht, Netherlands.
出版信息
Arch Dis Child Fetal Neonatal Ed. 1996 May;74(3):F177-81. doi: 10.1136/fn.74.3.f177.
AIMS
To describe the range of central venous oxygen saturation (ScvO2) values in stable newborn infants breathing room air; to examine the correlation between ScvO2 and arterial oxygen saturation (SaO2); to describe fractional oxygen extraction; and the shunt index, an estimate of the venous admixture.
METHODS
A prospective clinical observational study was made of 10 preterm infants breathing room air after the acute phase of respiratory distress syndrome, and with an umbilical venous catheter in situ. A fibre optic catheter remained in the right atrium for continuous measurement of oxygen saturation.
RESULTS
ScvO2, SaO2, blood pressure and heart rate were registered every 15 minutes. Fractional oxygen extraction and shunt index were calculated. SaO2 and ScvO2 were 93.4 (SD 3.7)% and 73.56 (5.25)%, respectively. In seven patients ScvO2 values correlated significantly with SaO2. Fractional oxygen extraction was 0.21 (0.04) and was significantly correlated with ScvO2. The shunt index was 24% (12) and was significantly correlated with SaO2.
CONCLUSIONS
Stable preterm infants breathing room air had an ScvO2 ranging from 65% to 82% (5th and 95th percentile), which corresponded to SaO2 > or = 86%. ScvO2 values were significantly correlated with SaO2 in most patients.
目的
描述呼吸空气的稳定新生儿中心静脉血氧饱和度（ScvO2）值的范围；研究ScvO2与动脉血氧饱和度（SaO2）之间的相关性；描述氧摄取分数；以及分流指数，即对静脉血掺杂的一种估计。
方法
对10例呼吸窘迫综合征急性期过后呼吸空气且脐静脉导管在位的早产儿进行了一项前瞻性临床观察研究。一根光纤导管留置在右心房以持续测量血氧饱和度。
结果
每15分钟记录一次ScvO2、SaO2、血压和心率。计算氧摄取分数和分流指数。SaO2和ScvO2分别为93.4（标准差3.7）%和73.56（5.25）%。7例患者的ScvO2值与SaO2显著相关。氧摄取分数为0.21（0.04），且与ScvO2显著相关。分流指数为24%（12），且与SaO2显著相关。
结论
呼吸空气的稳定早产儿ScvO2范围为65%至82%（第5和第95百分位数），这对应于SaO2≥86%。在大多数患者中，ScvO2值与SaO2显著相关。
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