Ghio L, Moroni G A, Piccoli P, Trombini M, Giani M, Angeli M, Edefonti A
Helv Paediatr Acta. 1982;37(1):17-26.
Hepatitis B virus (HBV) markers have been studied for 22 months in 16 haemodialysed patients, 60 relatives and 17 staff members of a paediatric haemodialysis unit, and in 9 children with chronic renal failure on conservative therapy. None of the 8 children negative for HBV markers and treated with specific immunoglobulins (HBIG) developed signs of hepatitis B. No hepatitis B occurred in 4 staff members after accidental infected needle prick and immunoprophylaxis, although one of them developed passive-active immunity. The immunoprophylaxis effectively prevented diffusion of HBV also in the relatives. Furthermore, HBsAg and HBeAg were found in urine samples of haemodialysed children with residual diuresis.
对一家儿科血液透析单位的16名接受血液透析的患者、60名亲属和17名工作人员以及9名接受保守治疗的慢性肾衰竭儿童的乙肝病毒（HBV）标志物进行了22个月的研究。8名HBV标志物阴性且接受特异性免疫球蛋白（HBIG）治疗的儿童均未出现乙肝迹象。4名工作人员在意外被感染针头刺伤并接受免疫预防后未发生乙肝，尽管其中1人产生了被动-主动免疫。免疫预防也有效地防止了HBV在亲属中的传播。此外，在仍有残余尿量的接受血液透析儿童的尿液样本中发现了HBsAg和HBeAg。
