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微球菌属菌株12B对邻苯二甲酸二甲酯的代谢

Metabolism of dimethylphthalate by Micrococcus sp. strain 12B.

作者信息

Eaton R W, Ribbons D W

出版信息

J Bacteriol. 1982 Jul;151(1):465-7. doi: 10.1128/jb.151.1.465-467.1982.

Abstract

During growth of Micrococcus sp. strain 12B with dimethylphthalate, 4-carboxy-2-hydroxymuconate lactone (CHML, X) and 3,4-dihydroxyphthalate-2-methyl ester (XI) were isolated from culture filtrates. CHML is the lactone of intermediate 4-carboxy-2-hydroxymuconate (IX). Accumulation of XI which is not a substrate for 3,4-dihydroxyphthalate-2-decarboxylase in strain 12B afforded an easy access to the preparation of 3,4-dihydroxyphthalate.

摘要

在微球菌属菌株12B利用邻苯二甲酸二甲酯生长的过程中,从培养滤液中分离出了4-羧基-2-羟基粘康酸内酯(CHML,X)和3,4-二羟基邻苯二甲酸-2-甲酯(XI)。CHML是中间体4-羧基-2-羟基粘康酸(IX)的内酯。XI不是菌株12B中3,4-二羟基邻苯二甲酸-2-脱羧酶的底物,其积累为制备3,4-二羟基邻苯二甲酸提供了便利途径。

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