Djenderedjian A, Tashjian R
J Clin Psychiatry. 1982 Jun;43(6):248-9.
Agoraphobia, now a clinically accepted entity (DSM-III) was first described more than 100 years ago in the psychiatric literature. Recently, it has been considered a syndrome, with phobia, anxiety and depersonalization being the prominent symptoms. Its etiology is not clear and different schools of thought have given different explanations for its causation. Few reports of recent origin have have described a close association between the intake and/or discontinuation of pharmacologic agents and the onset of the syndrome. The agents implicated were the tricyclic group. Our report describes another "antidepressant," d-amphetamine, which when discontinued by our patient, was followed by the full syndrome of agoraphobia.
广场恐惧症，如今是一种临床认可的病症（《精神疾病诊断与统计手册》第三版），早在100多年前就在精神病学文献中首次被描述。最近，它被视为一种综合征，恐惧、焦虑和人格解体是其突出症状。其病因尚不清楚，不同的思想流派对其成因给出了不同的解释。近期鲜少有报告描述药物制剂的摄入和/或停用与该综合征的发作之间存在密切关联。涉及的药物制剂是三环类药物。我们的报告描述了另一种“抗抑郁药”，即右旋苯丙胺，我们的患者停用该药后，随之出现了广场恐惧症的全部症状。
