依托咪酯三种制剂的评估。

Evaluation of three preparations of etomidate.

作者信息

Zacharias M, Clarke R S, Dundee J W, Johnston S B

出版信息

Br J Anaesth. 1978 Sep;50(9):925-9. doi: 10.1093/bja/50.9.925.

DOI:10.1093/bja/50.9.925

Abstract

Three formulations of etomidate were evaluated in unpremedicated patients undergoing minor gynaecological procedures. There was a high frequency of pain on injection (up to 50%) and excitatory phenomena (up to 95%) with all formulations. The frequency of excitatory phenomena was significantly greater than that after methohexitone. Recovery was rapid, but emetic sequelae were frequent and significantly more marked than after methohexitone.

摘要

对三种依托咪酯制剂在未接受术前用药的接受小型妇科手术的患者中进行了评估。所有制剂注射时疼痛发生率都很高（高达50%），兴奋现象发生率也很高（高达95%）。兴奋现象的发生率显著高于甲己炔巴比妥后的发生率。恢复迅速，但呕吐后遗症频繁，且比甲己炔巴比妥后更明显。