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依托咪酯三种制剂的评估。

Evaluation of three preparations of etomidate.

作者信息

Zacharias M, Clarke R S, Dundee J W, Johnston S B

出版信息

Br J Anaesth. 1978 Sep;50(9):925-9. doi: 10.1093/bja/50.9.925.

DOI:10.1093/bja/50.9.925
PMID:708560
Abstract

Three formulations of etomidate were evaluated in unpremedicated patients undergoing minor gynaecological procedures. There was a high frequency of pain on injection (up to 50%) and excitatory phenomena (up to 95%) with all formulations. The frequency of excitatory phenomena was significantly greater than that after methohexitone. Recovery was rapid, but emetic sequelae were frequent and significantly more marked than after methohexitone.

摘要

对三种依托咪酯制剂在未接受术前用药的接受小型妇科手术的患者中进行了评估。所有制剂注射时疼痛发生率都很高(高达50%),兴奋现象发生率也很高(高达95%)。兴奋现象的发生率显著高于甲己炔巴比妥后的发生率。恢复迅速,但呕吐后遗症频繁,且比甲己炔巴比妥后更明显。

相似文献

1
Evaluation of three preparations of etomidate.依托咪酯三种制剂的评估。
Br J Anaesth. 1978 Sep;50(9):925-9. doi: 10.1093/bja/50.9.925.
2
Effect of preanaesthetic medication on etomidate.
Br J Anaesth. 1979 Feb;51(2):127-33. doi: 10.1093/bja/51.2.127.
3
Venous sequelae following etomidate.
Br J Anaesth. 1979 Aug;51(8):779-83. doi: 10.1093/bja/51.8.779.
4
Etomidate in a new solvent. A clinical evaluation.依托咪酯新溶剂。临床评估。
Anaesthesia. 1977 Nov-Dec;32(10):996-9. doi: 10.1111/j.1365-2044.1977.tb09962.x.
5
Etomidate and methohexitone. A comparative clinical study in out-patient anaesthesia.
Anaesthesia. 1978 May;33(5):450-3. doi: 10.1111/j.1365-2044.1978.tb12463.x.
6
Relative potencies of methohexitone and etomidate.
Anaesthesia. 1979 Oct;34(9):904-5. doi: 10.1111/j.1365-2044.1979.tb08550.x.
7
Etomidate-fentanyl-air anesthesia.
Acta Anaesthesiol Belg. 1979;30 Suppl:89-100.
8
Recovery from day-case anaesthesia. Comparison between methohexitone, Althesin and etomidate.日间手术麻醉后的恢复。美索比妥、阿法沙龙/阿法多龙和依托咪酯之间的比较。
Br J Anaesth. 1982 Apr;54(4):447-51. doi: 10.1093/bja/54.4.447.
9
[Etomidate in Intralipid. A solution for pain-free injection].[依托咪酯溶于脂肪乳剂。一种用于无痛注射的溶液]
Anaesthesist. 1983 Oct;32(10):475-7.
10
Total intravenous anesthesia with etomidate. III. Some observations in adults.
Acta Anaesthesiol Belg. 1977;28(3):157-64.

引用本文的文献

1
Clinical and molecular pharmacology of etomidate.依托咪酯的临床与分子药理学。
Anesthesiology. 2011 Mar;114(3):695-707. doi: 10.1097/ALN.0b013e3181ff72b5.
2
Methohexitone or etomidate for induction of dental anaesthesia.
Can Anaesth Soc J. 1980 Nov;27(6):578-83. doi: 10.1007/BF03006891.
3
Alfathesin and etomidate for minor outpatient anaesthesia.用于小型门诊麻醉的阿法西辛和依托咪酯。
Can Anaesth Soc J. 1982 Nov;29(6):622-6. doi: 10.1007/BF03007751.
4
Adverse effects of intravenously administered drugs used in anaesthetic practice.麻醉实践中静脉注射药物的不良反应。
Drugs. 1981 Jul;22(1):26-41. doi: 10.2165/00003495-198122010-00002.
5
New drugs--boon or bane? Premedication and intravenous induction agents.新药——福还是祸?术前用药及静脉诱导剂。
Can Anaesth Soc J. 1983 Mar;30(2):166-73. doi: 10.1007/BF03009347.