饮食变化对活体血管中脂质水平和血小板血栓形成的影响。
The effects of changes in diet on lipid levels and platelet thrombus formation in living blood vessels.
作者信息
Honour A J, Carter R D, Mann J I
出版信息
Br J Exp Pathol. 1978 Aug;59(4):390-4.
The work reported here describes an in vivo study over several days in each animal, of the formation and behaviour of platelet thrombi in injured living blood vessels in response to topically applied adenosine diphosphate (ADP) in rabbits fed initially on normal diets, then on experimental "saturated" or "polyunsaturated" diets. The effects of these diets on triglyceride fatty acids and on cholesterol and triglyceride levels are reported. It may be of significance that in each experiment the "polyunsaturated" and "saturated" diets appeared to be associated with an increased sensitivity to ADP greater than observed in rabbits on a normal diet or in normal animals in other studies.
本文所报道的研究描述了一项在每只动物身上持续数天的体内研究，该研究观察了最初喂食正常饮食，然后喂食实验性“饱和”或“多不饱和”饮食的兔子，其受损活体血管中血小板血栓在局部应用二磷酸腺苷（ADP）时的形成及行为。文中还报道了这些饮食对甘油三酯脂肪酸以及胆固醇和甘油三酯水平的影响。或许具有重要意义的是，在每个实验中，“多不饱和”和“饱和”饮食似乎都与对ADP的敏感性增加有关，这种增加的敏感性比在其他研究中正常饮食的兔子或正常动物中观察到的情况更为明显。
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