使用克维姆试验材料的结节病白细胞迁移琼脂糖试验（LMAT）

Leukocyte migration agarose test (LMAT) in sarcoidosis using Kveim test material.

作者信息

Horsmanheimo M, Horsmanheimo A, Fudenberg H H, Siltzbach L E, McKee K T

出版信息

Br J Dermatol. 1978 Sep;99(3):263-70. doi: 10.1111/j.1365-2133.1978.tb01995.x.

DOI:10.1111/j.1365-2133.1978.tb01995.x

Abstract

The two-stage leukocyte migration agarose test (indirect LMAT), shown to be a sensitive in vitro assay for cell-mediated immunity, was used to study Kveim reactivity in vitro in patients with sarcoidosis. No Kveim-induced inhibition of leukocyte migration in agarose or Kveim-induced lymphocyte transformation in vitro was found in 23 patients with sarcoidosis, suggesting that the Kveim reaction is not an expression of cell-mediated immunity.

摘要

两阶段白细胞迁移琼脂糖试验（间接LMAT）被证明是一种用于细胞介导免疫的敏感体外检测方法，用于研究结节病患者的体外克维姆反应性。在23例结节病患者中，未发现克维姆诱导的琼脂糖中白细胞迁移抑制或克维姆诱导的体外淋巴细胞转化，这表明克维姆反应不是细胞介导免疫的一种表现。