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雄性恒河猴的脑细胞会积累3H-睾酮或其代谢产物。

Brain cells of the male rhesus monkey accumulate 3H-testosterone or its metabolites.

作者信息

Rees H D, Michael R P

出版信息

J Comp Neurol. 1982 Apr 10;206(3):273-7. doi: 10.1002/cne.902060307.

DOI:10.1002/cne.902060307
PMID:7085933
Abstract

Autoradiography was used to localize target cells for 3H-testosterone or its labeled metabolites in the brain of the rhesus monkey. Two castrated males were injected intravenously with 3H-testosterone (2 mCi/monkey) and were killed 1 hour later. In both animals, neurons that concentrated radioactivity in their nuclei were located in a well-circumscribed system that included the bed nucleus (n.) of the stria terminalis, medial preoptic n., suprachiasmatic preoptic n., anterior hypothalamic area, ventromedial hypothalamic n., cortical, medial, and basal accessory amygdaloid n., mesencephalic reticular n., and periaqueductal gray matter. In contrast to reports in some nonprimate mammalian species, little or no cellular labeling was observed in the lateral septum, arcuate n.-median eminence, motor nuclei of cranial nerves, or spinal cord.

摘要

利用放射自显影技术在恒河猴大脑中定位3H-睾酮或其标记代谢物的靶细胞。给两只去势雄性恒河猴静脉注射3H-睾酮(每只猴子2毫居里),1小时后处死。在这两只动物中,其细胞核中聚集放射性的神经元位于一个界限清楚的系统中,该系统包括终纹床核、内侧视前核、视交叉上核外侧视前核、下丘脑前区、下丘脑腹内侧核、皮质、内侧和基底杏仁核附属核、中脑网状核和导水管周围灰质。与一些非灵长类哺乳动物物种的报道不同,在外侧隔、弓状核-正中隆起、脑神经运动核或脊髓中几乎没有观察到细胞标记。

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Brain cells of the male rhesus monkey accumulate 3H-testosterone or its metabolites.雄性恒河猴的脑细胞会积累3H-睾酮或其代谢产物。
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