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大鼠脑线粒体和微粒体中的酰基辅酶A:sn-甘油-3-磷酸O-酰基转移酶

Acyl-CoA: sn-glycerol-3-phosphate O-acyltransferase in rat brain mitochondria and microsomes.

作者信息

Fitzpatrick S M, Sorresso G, Haldar D

出版信息

J Neurochem. 1982 Jul;39(1):286-9. doi: 10.1111/j.1471-4159.1982.tb04738.x.

DOI:10.1111/j.1471-4159.1982.tb04738.x
PMID:7086418
Abstract

The subcellular distribution of acyl-CoA: sn-glycerol-3-phosphate O-acyltransferase between brain mitochondria and microsomes was investigated. The activities associated with purified rat brain mitochondrial and microsomal preparations could be distinguished by differences in their acyl-CoA specificity, products of acylation, and sensitivity to N-ethylmaleimide, trypsin, acetone, and polymyxin B. It was concluded that both brain mitochondria and microsomes possess the acyltransferase.

摘要

研究了酰基辅酶A:sn-甘油-3-磷酸O-酰基转移酶在脑线粒体和微粒体之间的亚细胞分布。与纯化的大鼠脑线粒体和微粒体制剂相关的活性可以通过它们的酰基辅酶A特异性、酰化产物以及对N-乙基马来酰亚胺、胰蛋白酶、丙酮和多粘菌素B的敏感性差异来区分。得出的结论是,脑线粒体和微粒体都具有酰基转移酶。

相似文献

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Acyl-CoA: sn-glycerol-3-phosphate O-acyltransferase in rat brain mitochondria and microsomes.大鼠脑线粒体和微粒体中的酰基辅酶A:sn-甘油-3-磷酸O-酰基转移酶
J Neurochem. 1982 Jul;39(1):286-9. doi: 10.1111/j.1471-4159.1982.tb04738.x.
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The differential effect of polymyxin B1 on guinea pig lung mitochondrial and microsomal glycerophosphate acyltransferase.多粘菌素B1对豚鼠肺线粒体和微粒体甘油磷酸酰基转移酶的差异作用。
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Further distinguishing properties of mitochondrial and microsomal glycerophosphate acyltransferase and the transmembrane location of the mitochondrial enzyme.线粒体和微粒体甘油磷酸酰基转移酶的进一步鉴别特性以及线粒体酶的跨膜定位。
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