King R, Maas R, Gassner M, Nanda R K, Conover W W
Biophys J. 1978 Oct;24(1):103-17. doi: 10.1016/S0006-3495(78)85350-8.
A formalism based on the theory of Markov processes and suitable for the analysis of multiple internal motions in macromolecules is presented. Computer calculations of specific motional models for (13)C nuclear magnetic resonance (NMR) relaxation, treated as special cases of the proposed formalism, demonstrate the potential of this approach for discriminating between different motional models on the basis of NMR relaxation data.
提出了一种基于马尔可夫过程理论且适用于分析大分子中多种内部运动的形式体系。将(13)C核磁共振(NMR)弛豫的特定运动模型的计算机计算作为所提出形式体系的特殊情况进行处理,证明了该方法基于NMR弛豫数据区分不同运动模型的潜力。