Lehotzky K, Szeberenyi J M, Gonda Z, Horkay F, Kiss A
Neurobehav Toxicol Teratol. 1982 Mar-Apr;4(2):247-50.
Neurotoxic effects of the fungicide triphenyl-tin acetate were examined in pups of mothers treated perorally on day 7-15 of gestation. The gait and development of motor coordination did not differ from those of control animals, in spite of the high mortality rate of control pups during the nursing period. Spontaneous locomotor activity of treated pups at the age of 23 and 36 days was increased, however by the age of 90 days activity returned to control levels. Conditioned avoidance was acquired more rapidly, but was also extinguished sooner in animals born from, the nursed by poisoned mothers than in control.
在妊娠第7至15天经口给药的母鼠所产幼崽中检测了杀菌剂醋酸三苯基锡的神经毒性作用。尽管对照组幼崽在哺乳期死亡率很高，但步态和运动协调性发育与对照动物并无差异。经处理的幼崽在23天和36天时的自发运动活动增加，但到90天时活动恢复到对照水平。与对照组相比，由中毒母鼠哺育的幼崽习得条件性回避更快，但消退也更快。
