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恶性肿瘤患者和健康对照者的血清铁蛋白和骨髓含铁血黄素

Serum ferritin and bone marrow haemosiderin in patients with malignancies and in healthy controls.

作者信息

Jakobsen E, Engeset A, Sandstad B, Aas M

出版信息

Scand J Haematol. 1982 Mar;28(3):264-71. doi: 10.1111/j.1600-0609.1982.tb00525.x.

DOI:10.1111/j.1600-0609.1982.tb00525.x
PMID:7089485
Abstract

Serum ferritin has been analysed and bone marrow haemosiderin evaluated in 306 patients with malignancies, mostly lymphomas, and in 46 healthy controls. Also haemoglobin, serum iron, transferrin and liver enzymes were analysed simultaneously. 60% of the patients had serum ferritin above normal values and 20% had values above 1000 micrograms/l. There was a good correlation between serum ferritin and bone marrow iron both in the patients and in the controls, r = 0.67 and r = 0.77, respectively. There was a negative correlation between serum ferritin and haemoglobin concentration in the patients and a positive correlation in the controls. In patients with Hodgkin's disease serum ferritin was related to the stage of the disease.

摘要

对306例恶性肿瘤患者(主要为淋巴瘤患者)及46名健康对照者进行了血清铁蛋白分析和骨髓含铁血黄素评估。同时还对血红蛋白、血清铁、转铁蛋白和肝酶进行了分析。60%的患者血清铁蛋白高于正常值,20%的患者高于1000微克/升。患者和对照者的血清铁蛋白与骨髓铁之间均存在良好的相关性,分别为r = 0.67和r = 0.77。患者血清铁蛋白与血红蛋白浓度呈负相关,而对照者呈正相关。在霍奇金病患者中,血清铁蛋白与疾病分期有关。

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Serum ferritin and bone marrow haemosiderin in patients with malignancies and in healthy controls.恶性肿瘤患者和健康对照者的血清铁蛋白和骨髓含铁血黄素
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