Nicol E F, Irvine W J
Scott Med J. 1982 Apr;27(2):172-4. doi: 10.1177/003693308202700211.
Conventional preparation of thyrotoxic patients for surgery using thiouracils and iodides may not be possible because of either, inability to obtain satisfactory therapeutic levels of the drugs or idiosyncratic reactions to the drugs. An alterative regime using potassium iodide and propranolol in combination has previously been shown to be both safe and effective in the pre-operative control of mild to moderate thyrotoxicosis. The use of this combination in a patient with severe thyrotoxicosis is described. Potassium iodide and propranolol can be used successfully to prepare patients with all degrees of thyrotoxicosis for surgery.
由于无法达到药物的满意治疗水平或对药物的特异反应,使用硫脲类和碘化物对甲状腺毒症患者进行常规手术准备可能不可行。先前已证明,联合使用碘化钾和普萘洛尔的替代方案在术前控制轻度至中度甲状腺毒症方面既安全又有效。本文描述了该联合用药方案在一名重度甲状腺毒症患者中的应用。碘化钾和普萘洛尔可成功用于为所有程度的甲状腺毒症患者进行手术准备。