Srivastava D K
Toxicol Lett. 1982 Apr;11(1-2):135-9. doi: 10.1016/0378-4274(82)90118-7.
Copper (Cu), cadmium (Cd) and mercury (Hg) at concentrations of 12.5 mg/l, caused a decline in the glycogen level of liver, muscle, brain and kidney of Heteropneustes fossilis. A significant increase in the glycogen content of brain was caused by low concentrations (5 and 7.5 mg/l) of both Cd and Hg 5 mg/l Cu raised the kidney glycogen level, while the same dose of Hg raised liver glycogen. It is suggested that heavy metals in low concentrations act through the endocrine system, creating hormone and/or enzyme imbalance.
浓度为12.5毫克/升的铜(Cu)、镉(Cd)和汞(Hg)导致了印度胡鲶肝脏、肌肉、大脑和肾脏中糖原水平的下降。低浓度(5和7.5毫克/升)的Cd和Hg都会导致大脑中糖原含量显著增加;5毫克/升的Cu会提高肾脏中的糖原水平,而相同剂量的Hg会提高肝脏中的糖原水平。研究表明,低浓度的重金属通过内分泌系统起作用,造成激素和/或酶失衡。