Ivanov P K, Tkacheva G A
Vopr Onkol. 1982;28(4):29-34.
Radioimmunological tests for carcinoembryonic antigen, antibodies to thyroglobulin, thyrotropin of pituitary, thyroxin and triiodothyronine were run in healthy subjects and patients suffering from cervical thyroid and extrathyroid neoplasms, e. g. nodular goiter, adenoma, cancer, chronic thyroiditis, lymphadenitis, neurinoma, hemangioma and thyrotoxicosis. The thyroid was scanned with 131I or 99mTcO4 in all cases. Scanning of thyroid in the first stage of screening for malignant tumors because "warm" or "hot" foci in scanograms of cases of malignant nodes are very rare. In patients with "cold" thyroid nodes, detection of thyroglobulin antibodies points to thyroiditis since such antibodies are not found in all other cases. None of the indices showed any differences in cases of nodular goiter and "cold" adenoma. Coefficient sTTH/bTTH (ratio of thyroliberine-stimulated level of pituitary thyrotropin to basal one) is decreased, while coefficient (Formula: see text) and blood plasma level of carcinoembryonic antigen are increased in patients with thyroid cancer as compared with benign tumors.